A hemothorax involves blood in the pleural space. Hemothorax can be caused by cancer, a penetrating injury to the chest, a pulmonary embolism (blood clot in the lungs), and many other causes. A pneumothorax refers to air in the pleural space. Like a hemothorax, this may cause difficulty breathing.Click to see full answer. Herein, can a Hemothorax cause a pneumothorax?Hemothorax is when blood collects between your chest wall and your lungs. This area where blood can pool is known as the pleural cavity. Hemothorax can be caused by many of the same things that cause pneumothorax. Pneumothorax happens when too much air gets between your chest wall and lungs. what is the most common cause of a Hemothorax? The most common cause of hemothorax is chest trauma. Hemothorax can also occur in people who have: Blood clotting defect. Chest (thoracic) or heart surgery. Also Know, what is a Hemothorax? A hemothorax (derived from hemo- [blood] + thorax [chest], plural hemothoraces) is an accumulation of blood within the pleural cavity. Hemothoraces may be treated by draining the blood using a chest tube, but may require surgery if the bleeding continues.What is the difference in placement location of a chest tube when inserted for a Hemothorax versus pneumothorax?Usually, for pneumothorax, a straight tube is placed toward the apex. For hemothorax or pleural effusion, typically a straight tube is placed posterior and toward apex and/or a right-angled tube can be placed at the base of lung and diaphragm.